Indolizidine, Antiinfective and Antiparasitic Compounds fromProsopis glandulosavar.glandulosa
نویسندگان
چکیده
منابع مشابه
Human Monoclonal Antibodies as a New Class of Antiinfective Compounds
The concept of using " magic bullets " in the fight against infectious diseases was originally proposed by Paul Ehrlich, one of the founding fathers of immunology and of the basis of anti-infective therapy [1]. These " magic " compounds should have been able to target microbes without harming the infected host. Actually, this concept is the mainstay of antiinfective therapy, as we still know it...
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This review covers the isolation, structure determination, synthesis, chemical transformations and biological activity of indolizidine and quinolizidine alkaloids from microbial, plant and animal sources. Included in the review are the hydroxylated indolizidines lentiginosine, swainsonine, castanospermine and their analogues; alkaloids from animal sources, including ants, amphibians and beetles...
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Fungi are a newly emerging source of peptide antibiotics with therapeutic potential. Here, we report 17 new fungal defensin-like peptide (fDLP) genes and the detailed characterization of a corresponding synthetic fDLP (micasin) from a dermatophyte in terms of its structure, activity and therapeutic potential. NMR analysis showed that synthetic micasin adopts a "hallmark" cysteine-stabilized α-h...
متن کاملAntiinfective properties of human milk.
The unfavorable effects of neonatal immunodeficiency are limited by some naturally occurring compensatory mechanisms, such as the introduction of protective and immunological components of human milk in the infant. Breast-feeding maintains the maternal-fetal immunological link after birth, may favor the transmission of immunocompetence from the mother to her infant, and is considered an importa...
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ژورنال
عنوان ژورنال: Journal of Natural Products
سال: 2009
ISSN: 0163-3864,1520-6025
DOI: 10.1021/np800653z